A total of four matches will be played across two weekends - two each on September 13 and September 20.
"Due to the ongoing COVID-19 pandemic, the fixtures will take place behind closed door," a statement from Cricket Scotland said.
“I am excited we are able to confirm a revised Regional Series for the month of September," Gus Mackay, chief executive of Cricket Scotland, said. "We have worked hard with the regional teams and selected venues across Scotland to get these matches confirmed for both the men’s and women’s series.
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Steve Knox, head coach of the women's team, said he would use the series in order to finalise the national team's winter training squad.
Fixtures:September 13: Eagles v Stormers (two T20 matches at Strathmore)
September 20: Eagles v Stormers (two T20 matches)